Interleague
Starting pitchers
Giants vs Lions: Tokyo Dome 5:45 pm, 4:45 am EDT
Yuki Takahashi (6-1, 2.39) vs Wataru Matsumoto (4-3, 2.42)
Swallows vs Eagles: Jingu Stadium 5:30 pm, 4:30 am EDT
Yuto Kanakubo (3-1, 1.99) vs Takahiro Shiomi (-)
BayStars vs Hawks: Yokohama Stadium 5:45 pm, 4:45 am EDT
Michael Peoples (2-1, 2.45) vs Shota Takeda (3-3, 2.76)
Dragons vs Marines: Vantelin Dome (Nagoya) 5:45 pm, 4:45 am EDT
Yuya Yanagi (4-1, 1.62) vs Kota Futaki (2-2, 3.60)
Tigers vs Buffaloes: Koshien Stadium 6 pm, 5 am EDT
Yuki Nishi (3-3, 3.26) vs Taisuke Yamaoka (2-4, 4.09)
Carp vs Fighters: Mazda Stadium 6 pm, 5 am EDT
Daichi Osera (2-1, 1.71) vs Naoyuki Uwasawa (4-2, 3.24)
Active roster moves 5/31/2021
Deactivated players can be re-activated from 6/10
Central League
Activated
None
Dectivated
| Tigers | P | 41 | Shoki Murakami |
| Dragons | C | 58 | Kota Ishibashi |
| Carp | P | 99 | Dovydas Neverauskas |
| Swallows | P | 43 | Albert Suarez |
| Swallows | IF | 65 | Yu Matsumoto |
Pacific League
Activated
None
Dectivated
| Marines | IF | 55 | Adeiny Hechavarria |
| Marines | OF | 51 | Koki Yamaguchi |
| Lions | P | 25 | Katsunori Hirai |
| Lions | OF | 35 | Gakuto Wakabayashi |
| Eagles | C | 67 | Takahiro Shimotsuma |
| Fighters | P | 44 | Robbie Erlin |
